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Hmm I was thinking that maybe you can use the medicine or cure that the guy who you give gold coins to. It would be mean you have to carry the cure to the past and give it them. But I always help Antonia.
The lore reason for why this doesn't work is that Giangio tells you the cure is unstable and has to be administered ASAP. It's safe to assume that by the time you reach the people you want to give this to in the past, it has "expired".