If you are using nvidia fast vsync please reset it to the default (v-sync on/default). https://beebom.com/what-is-nvidia-fast-sync-enable/ (but turn it off :)
https://bugzilla.libsdl.org/show_bug.cgi?id=3618

Disabling MultiSampling/MSAA has been effective for a number of users.
This can be done in the options (if you can access them), the --disableMultisampling launch option or the 4th start option (soon to be available, currently only works on the testing branch)
Or by forcing it off in the videocard control panel.

If you are using an AMD video card try turning off OpenGL Triple buffering for Staxel, this has been reported by the community to fix some blackscreen issues.
You may have to do it in the global profile as some reports say it doesn't work on the games profile in AMD Radeon Settings

There are reports that Rivatuner will also cause a black screen.
https://steamhost.cn/steamcommunity_com/app/405710/discussions/1/2860219962088498345/?ctp=3

Please also see https://steamhost.cn/steamcommunity_com/sharedfiles/filedetails/?id=1620515354

(If you have an nvidia graphics card) Go to the NVIDIA Control Panel -> Manage 3D Settings and press the 'Restore' button to reset any possible issues with driver settings. also resolved this for some users.