In Steam Overlay, my ''visual'' mouse is not aligned with my ''actual'' mouse
So, when a friend invites me to a game via the Steam Overlay and I go in to click on it, my visual mouse is over the button, I click and nothing happens.

By moving my mouse around on screen, I identified that it's just in another place completely.

I've tried the compatibility fix in Steam Properties
I've tried to uncheck the setting in Steam settings