When I try to open Spider-Man 2 after restarting the PC, the game crashes after some seconds. When I try to open it again I get the message "PCWARNING_MISSINGFILE"

When I try to open another game after this happend I got the message "An error occurred while starting this game: Invalid platform".
I need to restart the PC to start every other game.

I also tryed to reinstal Spider-Man 2 but this changes nothing.