Step 1: Once you've launched the game, go into settings and set the Kinetigen key to something you're comfortable hitting repeatedly. (If fine with spacebar, leave as default (Future reference to kinetigen keybind will be "Spacebar"))
Step 2: Exit settings, and move cursor over the kinetigen button.
Step 3: If Right handed, place left hand on "Spacebar", and keep your right hand on your mouse. (If Left handed, place right hand on "Spacebar", and keep left hand on mouse.)
Step 4: Place the middle and index fingers of the hand that is on the mose over the selection click mouse button (Left click for Right handed people, and Right click for Left handed people.), and the ring and pinky fingers on the context menu click button (Right cick for Right handed, and Left click for Left handed.)
Step 5: Begin mashing the two mouse buttons and the "Spacebar", using alternation of the two fingers on each of the mouse buttons to minimize the strain on your hands.
Step 6: Keep at this until you are at a point where you get 100 Million+ money per hour and a half while the program is closed.
Step 7: Once Step 6 is satisfied, simply open up the program every 1.5 hours, spend the accumulated money on more buildings and upgrades, and close it.
Step 8: Repeat Step 7 until you win.