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My go-to startup is simply to get 10 points in Toughness ASAP for the +30 health regen and then drop 2 or 3 skillpoints in the Health tree where you get +20 health regen below 50% max health. From that point on you pick your fav weapon and start dumping everything into damage damage damage.
Psyker and Assassin simply are not as forgiving. 50 health regen you can reach by Charlevel 10 is just so comfortable.