1: Remember to save. a lot. Make backups along with your main save. Update all of your saves whenever you're in your territory, defeat an invasion (it's just annoying to have to defeat the same invasion twice if you die to another enemy later), get invaded (you don't want to lose progress if the invasion does rarely overpower you), approach randomly generated missions (do I need to explain this?), perform a major upgrade/rebuild of one of your techs, or just do anything generally important.

2: Avoid fighting more than one tech that's even just half of your size at once. If you get attacked by at least two decently-sized enemies at once, run away. No matter how many batteries you have, or how much damage you can wreak in a short time span, enough medium-sized enemies can still whittle away your shields quite quick. Especially if they have explosive weaponry. Also, if they have some of the more powerful explosive weapons, like the Big Bertha Cannon, just kill them from a distance with missiles.

3: Try to save up enough money to replace your Tech if you do die, because bitter experience has taught me that death late game when you have a fancy and expensive tech is not only likely, but inevitably going to happen when you've forgotten to save for the past 10 minutes.

Okay, so this is the main part of the strategy, which I have also had the most time to refine. This part is quite important for this, so make sure you don't miss anything.

The start of the game is basically the exact same as it normally is, except for a few key differences.

For one thing, when you first reach a trading station, complete the Turret Defence mission, as it unlocks the inventory, which is especially important for dropped blocks. If you don't have an SCU, just anchor all the blocks you want to pick up and then send it all to your inventory from the radial menu.

When you get license missions, don't complete them until you max out your license for the previous corporation. In case you don't know, the max levels for all of the corporations are 4, except for GSO, which has a max level of 6. The reason you should do this is because the less licenses you have, then the techs for the other corporations won't spawn, so you can get XP faster.

While maxing out licenses, you will definitely have lots of time to complete other randomly generated missions. I have a priority system for those.

Priority 1: Base Capture
These missions can give you lots of blocks and even pre-made base snapshots if you need them.
Oh, don't forget the crate.
Priority 2: Tech Defence
These missions give you an allied AI tech. and crate.
Priority 3: Delivery Crate
These missions give you crates, and are surprisingly frequently (at least in my experience) not ambushes, and when they are they can usually be pretty easily destroyed. They also give you a lot of SCUs. SCUs make picking up dropped blocks a lot easier than the aforementioned anchor-storage technique. And it also tends to give a lot of other good stuff, like Big Bertha Cannons when you reach GSO level 5.
Priority 4: Enemy Killing
These missions give you lots of enemies to kill, which means lots of XP.
Priority 5: Racer Tech
These missions give you only one enemy tech to kill and force you do to it in a time limit. It's basically only good for money.

This point is by the time you max out your GSO license. This is a section all about designing your Techs to be as inhumanly overpowered as possible.

1: Forget about solar panels. They suck.
Solar panels are good power generation in the early game, but when you unlock Mobile Furnace Generators, you should just use them instead. Just connect them up to your resource collectors.
2: Remember me mentioning how you can make money really fast while just going through a forest earlier?
To do that, just connect a Mobile Delivery Cannon to your resource collectors. Shocking, I know.
But you can improve it even more by attaching a Pacemaker to it and setting it to maximum speed. this is actually surprisingly effective. Then just destroy every tree you come across and watch as your Block Bucks balance steadily increases. Once you unlock the Venture Mobile Refinery, you can improve this yet again.
3: MISSILES. JUST MISSILES.
GSO Missile Batteries are incredibly effective long-range compared to other homing explosive ordnance. You can actually damage enemies outside of their attacking range by just shooting in their general direction. The 1x2 Hawkeye missile launchers are better, taking up less space while also firing faster.

This is some extra information for around the point which you would start doing Reticule Research missions.

1: Plasma weapons are incredibly overpowered against blocks and shields.
If you've gotten the Reticule Research Talon Laser, then absolutely do use it on your main tech. That thing goes through shields with a decently sized energy supply like a flaming chainsaw through abnormally flammable wood, and goes through most blocks even more effectively. If you don't, the Better Future laser weapons seem to be nearly as good if not just as good, or better. They are far more numerous by the time you reach this point.
2: Use as many Better Future weapons as possible. I don't know why I didn't do it earlier, given that it's one of the end-game corporations.