I'm actually not entirely sure whether or not it's advisable to make scenarios directly based on other properties, but I don't think anyone'd care. Alternatively, some knockoff version could be made.

My suggestion is to make a scenario based on the genestealers from Warhammer 40 000. Genestealers are infiltrator creatures sent out by tyranid hive fleets(space-faring super organisms that devour life on planets).
See lore pages:
http://warhammer40k.wikia.com/wiki/Genestealer
http://warhammer40k.wikia.com/wiki/Genestealer_Cult
http://wh40k.lexicanum.com/wiki/Genestealer_Cult
Genestealers are alien monsters who infiltrate society, and infect citizens with genestealer DNA, causing any offspring they produce to become increasingly genestealer-like with each generation. These purestrain genestealers and various genstealer hybrids will gather in underground cults from which they plan try to infect more people and undermine society. The oldest of the purestrain genestealers will develop into a genestealer patriarch who is worshiped by the cult, and who also develops strong psychic powers that he can use as a beacon to attract the tyranid hive fleet.

I Imagine it could have at least 2 victory conditions, either by taking over the planet with the cult, or by developing a strong patriarch who can attract the hive fleet to come devour the planet, if he can make his beacon strong enough for long enough.

I feel as if there is potential to adapt this into a Plague Inc scenario, and I can't find anyone who's already done it.