In order of most recently updated last I checked:

- Levelhead has 1 slot to evoke lots of meager 0-cost orbs.
- Slime boss from downfall has skills that exhaust to summon slimes.
- Templar manages 2 slots and gets a bonus for matching pairs.
- Dark knight from aigis basically has lightning but it's a minor mechanic.
- Librarian channels inert elements that are evoked by the cast keyword.
- Goldenglow manages 1 orb type for both enemies and yourself.
- Evolution has lots of orb types and card text but nifty cross-orb synergy.

There are a few more that make use of the orb framework but implement it in very different ways so I don't directly associate them with defect.

One of the character from the VupShion mod (its nsfw but no nudity, just swimsuits) has 4 turrets that she levels up through fights (she retains the level from one fight to the next), one apply a dot, one a stacking debuff, one buffs you (strenght, dex and energy every round) and the last one give you shield (armor that doesn't go away each turn). Realistically you can only get 1 or two turret up to a decent level each round so you need to chose what you prefer.

The character is really good so it makes act 3 and 4 a lot easier but the mod added two extra boss fight at the end that are way harder (the last fight does 400 to 500 dmg per round its fairly hard)