Sweet Flower gives you an extra energy but more importantly it turns the entire map into question marks. Mystery Machine then gives you +1 strength or dex permanently for each question mark you visit.
It's a fun synergy but Mystery Machine shouldn't be common given how broken this is.

I don't know what new game plus version I was up to but the lord of annihilation had 80k health and still wasn't much of a threat given the massive stats this combo adds up.