Great mod! The characters are really enjoyable, and are well thought out. However, I would like to point out that the unlocks feel... unremarkable. Most of them have a basic, broken effect with no strings attached. While I'm not opposed to characters having broken or basic unlocks, I think that the items in this mod could use some work. Here are some suggestions:

Make Cherished Memories only charge with trinkets, each charging 2 bars. Alternatively, a mom/dad related item could be spawned at the cost of one of your own items disappearing. That way, Cherished Memories could act like a D4-lite, where you don't want to reroll your entire build, but only a few items.

Change Revolution to only afflict 25-50% of a room, making the "revolution" name fit much more, alongside making the item more balanced.

Locked Memories should give a reward of some kind when opening Red Rooms. Maybe a stat boost?

Anarchist's Payback should only activate a set number of times total, maybe 2-3.

Cycle of Abuse should afflict a maximum of 3 other enemies per hit. These enemies could be anywhere in the room instead of just close to the initial target, making for a more interesting interaction with the item.

Tenacity: I feel that this is too similar to Evil Charm. Instead of scrapping the entire item, you could give the player a boost of some kind if they were recently afflicted with a status effect.

Overall, this mod is super fun. I wish you luck in any future modding endeavors!