I have found an interesting behaviour when having Scaria Contamination Patch installed alongside Vanilla Quests Expanded - The Generator:

If you have the nuclear powered version, at some point it allows you to switch into "hazard mode". To imitate radiation effects, pawns that wander in the vicinity of the generator are supposed to slowly get a toxic buildup.
However with the Scaria Contamination Patch, they instantly get "Viral Load" instead.
Worse, it progresses at a crazy rate, after 10-20 seconds you can have 10%+ progress.
Few ingame hours and half of colony is dead. And there does not seem to be any way to cure it - not possible to tend, no operation present. Basically pretty much game over.