Exception Log said this and the console and Output logs end with this mod so I would try it out.

NullReferenceException: Object reference not set to an instance of an object
RainWorldGame.Update () (at <1014ff9a5d9941ab9e645d4f5c9384a5>:0)
MainLoopProcess.RawUpdate (System.Single dt) (at <1014ff9a5d9941ab9e645d4f5c9384a5>:0)
RainWorldGame.RawUpdate (System.Single dt) (at <1014ff9a5d9941ab9e645d4f5c9384a5>:0)
DMD<>?-1251647872.Trampoline<RainWorldGame::RawUpdate>?1995403264 (RainWorldGame , System.Single ) (at <1ecbec0cbcfe4528b6bd9b137e7727bb>:0)
CrazyWeaponsPlugin.CrazyWeaponsMod.RawUpdatePatch (On.RainWorldGame+orig_RawUpdate orig, RainWorldGame self, System.Single dt) (at <742f51e28fee4114a0f6023ffc606bfb>:0)
DMD<>?-1251647872.Hook<RainWorldGame::RawUpdate>?1435189248 (RainWorldGame , System.Single ) (at <339dd0b52bc64a7286c03c307bc24e45>:0)
DMD<>?-1251647872.Trampoline<RainWorldGame::RawUpdate>?-852242432 (RainWorldGame , System.Single ) (at <d98cff191e8c409b8bab607a87f0c365>:0)
Pom.Pom.RainWorldGameRawUpdate (On.RainWorldGame+orig_RawUpdate orig, RainWorldGame self, System.Single dt) (at <f26f3a5efaa94b93bb1c8a4d34b6c44c>:0)
DMD<>?-1251647872.Hook<RainWorldGame::RawUpdate>?419626496 (RainWorldGame , System.Single ) (at <44772a1821324c9c8c97ae08511aed66>:0)
DMD<Update>?-1251647872._ProcessManager::Update (ProcessManager this, System.Single deltaTime) (at <8a62549be6b84734b7dabb897ce1225d>:0)
DMD<>?-1251647872.Trampoline<ProcessManager::Update>?-1468483584 (ProcessManager , System.Single ) (at <98d073a758024ca18744634d5925b8ee>:0)
MinimalistMultiplayer.DSClient.ProcessManager_Update (On.ProcessManager+orig_Update orig, ProcessManager self, System.Single deltaTime) (at <ff5779e080aa45918b48dd1abbaed333>:0)
DMD<>?-1251647872.Hook<ProcessManager::Update>?256501760 (ProcessManager , System.Single ) (at <4f07d2a2a06145f198a074d84950b80f>:0)
DMD<Update>?-1251647872._RainWorld::Update (RainWorld this) (at <8cf4e0cffe6c41c5a943beeb4a4c644e>:0)
DMD<>?-1251647872.Trampoline<RainWorld::Update>?2042975232 (RainWorld ) (at <52b85da92554497c844fc83eef99248d>:0)
RainWorldTryCatch.RainWorldTryCatchPlugin.<OnEnable>b__0_0 (On.RainWorld+orig_Update orig, RainWorld self) (at <532d00fc174848708ef7c04b6e6addad>:0)
UnityEngine.Debug:LogException(Exception)
RainWorldTryCatch.RainWorldTryCatchPlugin:<OnEnable>b__0_0(orig_Update, RainWorld)
DMD<>?-1251647872:Hook<RainWorld::Update>?-527006720(RainWorld)
DMD<>?-1251647872:Trampoline<RainWorld::Update>?-1381571584(RainWorld)
Guardian.LogHooks:RainWorld_Update(orig_Update, RainWorld) (at E:/RainWorldModding/Guardian/src/plugin/Hooks/LogHooks.cs:23)
DMD<>?-1251647872:Hook<RainWorld::Update>?1711405568(RainWorld)


Log Output Ended in this: [Debug :Barrel of Scavs] Made Leech ID.-1.12811 drop everything while dragged into den
[Debug :Barrel of Scavs] Made Leech ID.-1.12811 drop everything while dragged into den

Occurred in Waterfront Facility with a good handful of mods. If you need more data I can give the mod list. The freeze takes a while so.