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D18

Because what The Binding of Isaac really needs is another dice.

Rerolls coins into other coins, chests into other chests, hearts into other hearts, pill into other pills, and cards and runes into other cards and runes.

Reroll is based on the same chances as normal pickup drops. For example, coins will usually reroll into pennies but have a small chance to reroll to nickels, an even smaller chance to reroll into dimes etc.

Requires 4 charges.