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kz_thrombosis

Deep vein thrombosis (DVT) occurs when a blood clot (thrombus) forms in one or more of the deep veins in your body, usually in your legs. Deep vein thrombosis can cause leg pain or swelling, but also can occur with no symptoms.

Deep vein thrombosis can develop if you have certain medical conditions that affect how your blood clots. It can also happen if you don't move for a long time, such as after surgery or an accident, or when you're confined to bed.

Deep vein thrombosis can be very serious because blood clots in your veins can break loose, travel through your bloodstream and lodge in your lungs, blocking blood flow (pulmonary embolism).
Symptoms
Deep vein thrombosis signs and symptoms can include:

Swelling in the affected leg. Rarely, there's swelling in both legs.
Pain in your leg. The pain often starts in your calf and can feel like cramping or soreness.
Red or discolored skin on the leg.
A feeling of warmth in the affected leg.

Deep vein thrombosis can occur without noticeable symptoms.

Risk factors that contribute to thrombosis include:

Immobilization
Hypercoagulability
Vessel wall damage
Age
Surgery (especially orthopedic surgery and total knee replacement)
Cancer
Heredity (including the Factor V Leiden genetic mutation)
Pregnancy
Increased estrogen levels (due to oral contraception or hormone replacement therapy)
Obesity
Smoking

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