I play with the Marksmanship Mod enabled, which adds a fifth skill for ranged weapons, but doing so creates a problem when selecting Bethany as one of the starting agents; with the Marksmanship mod enabled, her Cryogun requires a Ranged stat of 2 in order to use, but she starts with Ranged 1, meaning that until you pour credits into a Ranged upgrade, that gun of hers is just a cluttered item slot.

I initially wondered whether the gun itself was bugged because if Steelcrow's Agents Cohesion Tweaks is enabled, you don't actually get a message saying that you can't fire the gun because your Ranged stat is too low, the pop-up simply says "3 KO" but the shoot option is still disabled.

Anyway, given that all agents should be usable right out of the gate without the need to immediately put credits into them, unless there's a specific reason why Bethany starts with 1 Ranged, you should probably lower the gun's requirement to 1 Ranged. Either that or make her start with a Ranged stat of 2 and lower her starting Hacking stat to 1 if you want to avoid giving agents more than Day 1 stat boost.

EDIT: Okay, I took a quick peek inside the agentsDefs and I noticed that you did put a "Markmanship = 2" on both versions of Bethany, which for some reason is not reflected in the in-game menu. (likewise, Archimedes is supposed to have Ranged on 2 for one of his variations, but both of them start out with a Range of 2 in my in-game menu)