BLOODY_CROWN, "Spawns a blood donation machine in treasure rooms

FRAGMENTED_CARD, "Entering a new secret room grants half a soul heart

LUCKY_SACK, "Secret rooms contain a bonus grab bag

ROSARY_BEAD, "Spawns an extra choice in angel rooms #The Bible activates Crack the Sky

TELESCOPE_LENS, "Entering a new planetarium cycles the item between 2 choices

BROKEN_GLASSES, "Planetariums have a blind choice

BUTT_PENNY, "Drops one of your pennies in a random spot in uncleared rooms

HAIRPIN, "Grants a pip of charge when entering an uncleared big room

LIBERTY_CAP, "Uses Wavy Cap when entering an uncleared room while not dizzy

MOMS_LOCK, "5% chance to use The High Priestess when entering an uncleared room #+5% chance per Mom item

KEEPERS_BARGAIN, "Shop items are 1 cent cheaper

BROKEN_ANKH, "Grants half a soul heart when entering a new level

MOMS_PEARL, "Grants half a soul heart when entering a new level

AAA_BATTERY, "Grants 2 pips of charge when entering a new level

CAINS_EYE, "Reveals a boss room when entering a level

COUNTERFEIT_PENNY, "Spawns a crane game when entering a new level

BLESSED_PENNY, "Spawns a fortune telling machine when entering a new level

SWALLOWED_PENNY, "Spawns a beggar when entering a new level

BLOODY_PENNY, "Spawns a devil beggar when entering a new level

FLAT_PENNY, "Spawns a key master when entering a new level

BURNT_PENNY, "Spawns a bomb bum when entering a new level

CHARGED_PENNY, "Spawns a battery beggar when entering a new level

CURSED_PENNY, "Spawns a hell game when entering a new level

MAGGYS_FAITH, "Spawns a confessional when entering a new level

ROTTEN_PENNY, "Spawns a rotten beggar when entering a new level

MATCH_STICK, "Spawns a bomb pickup when entering a new level

RUSTED_KEY, "Spawns a key when entering a new level

CHILDS_HEART, "Spawns a heart when entering a new level

LUCKY_TOE, "Spawns a random pickup when entering a new level

SAFETY_CAP, "Spawns a pill when entering a new level #Eating a pill heals half a heart

ACE_SPADES, "Spawns a card when entering a new level #Playing cards are more powerful

STRANGE_KEY, "Spawns an item choice when entering Hush floor

ADOPTION_PAPERS, "Sells a familiar for 15 cents in the starting room

MYOSOTIS, "25% chance for pickup from previous floor to duplicate

KARMA, "Spawns an unjammed donation machine when entering a new level

POKER_CHIP, "Gambling gives bonus prizes #Shops are replaced by arcades

LOST_CORK, "Enemies spawn a puddle of creep on death

CHEWED_PEN, "Slowed enemies spawn a puddle of slowing ink on death

PINKY_EYE, "Poisoned enemies spawn a poison cloud on death

LIGHTER, "Set nearby enemies on fire when damaged #Burning enemies spawn a flame on death

ISAACS_FORK, "Killing a beggar or shopkeeper heals half a heart

POLISHED_BONE, "Bonies spawn 3 bone orbitals on death

PURPLE_HEART, "Champion monsters drop a random bonus pickup

KIDS_DRAWING, "25% chance to spawn a blue fly when an enemy dies #+25% chance per Guppy item

BLISTER, "5% chance to shoot fist tears

OUROBOROS_WORM, "Tears are piercing

WIGGLE_WORM, "10% chance to shoot poison tears

RING_WORM, "10% chance to shoot burning tears

SUPER_MAGNET, "5% chance to shoot Lodestone tears

HOOK_WORM, "10% chance to shoot Cricket's Body tears

NOSE_GOBLIN, "Booger tears are always homing

BLACK_LIPSTICK, "Turns soul heart spawns into black hearts

BIBLE_TRACT, "Turns soul heart spawns into eternal hearts

MOMS_LOCKET, "Turns half soul hearts into full soul hearts

EQUALITY, "Basic coins/keys/bombs spawn as the one with the lowest count

GOLDEN_HORSE_SHOE, "5% chance for pickups to be golden variants

OLD_CAPACITOR, "20% chance for batteries to be Mega Batteries

CRYSTAL_KEY, "20% chance to turn key drops into Cracked Key

BROKEN_MAGNET, "Open normal, spiked, mimic and wooden chests when they spawn

LEFT_HAND, "Red chests grant half a black heart when opened

PAPER_CLIP, "Spawns a random bonus pickup when opening a locked chest

GILDED_KEY, "Spawns a random bonus pickup when opening a locked chest

FISH_HEAD, "Clearing a room spawns a blue fly

FISH_TAIL, "Clearing a room spawns 2 blue flies

LOUSE, "Clearing a room spawns a blue spider

APPLE_OF_SODOM, "Clearing a room spawns a blue spider

MYSTERIOUS_CANDY, "Clearing a room spawns a normal dip

BAT_WING, "Clearing a room has a 1/3 chance to spawn a friendly One Tooth

GOAT_HOOF, "Clearing a room has a 1/3 chance to spawn a friendly Goat

BLUE_KEY, "Clearing a room has a 1/3 chance to spawn a friendly Blue Gaper

HOLLOW_HEART, "Clearing a room has a (bone hearts/4) chance to spawn a bone orbital

TONSIL, "Clearing a room spawns a friendly Leper Flesh

WATCH_BATTERY, "Grants an extra pip of charge when clearing a big room

STEM_CELL, "Heals half a red heart when clearing a big room

BLACK_FEATHER, "Spawns an extra choice in devil rooms

FILIGREE_FEATHERS, "Deals spawn past Womb

BETHS_FAITH, "10% chance to grant a wisp when clearing a room

BETHS_ESSENCE, "10% chance to grant a wisp when clearing a room

MECONIUM, "1/10 of rocks are replaced by poop

PETRIFIED_POOP, "10% of rocks are replaced by poop

LIL_LARVA, "10% of rocks are replaced by poop

BROWN_CAP, "Explosion immunity #10% of rocks are replaced by poop

STUD_FINDER, "5% of rocks are turned into fool's gold

CHILD_LEASH, "50% chance to replace shop item with familiar

DUCT_TAPE, "50% chance to replace shop item with familiar

EXTENSION_CORD, "50% chance to replace shop item with familiar

BABY_BENDER, "50% chance to replace shop item with familiar

FORGOTTEN_LULLABY, "50% chance to replace shop item with familiar

THE_TWINS, "50% chance to replace shop item with familiar

WALNUT, "Explosion immunity until the explosion that breaks the trinket

CALLUS, "Sacrifice room and Sanguine Bond spikes deal half heart damage")

MOMS_TOENAIL, "Mom's Foot can't damage Isaac

CROW_HEART, "Removes -99% deal chance penalty from taking red heart damage

WISH_BONE, "Taking damage spawns a bone orbital

FINGER_BONE, "Taking damage spawns a bone orbital

RED_PATCH, "Use Larynx when taking damage

GIGANTE_BEAN, "Use Butter Bean when taking damage

WOODEN_CROSS, "Uses Holy Card when damaged at low health

MISSING_POSTER, "Uses Holy Card when damaged at low health

CURSED_SKULL, "Uses Holy Card when damaged at low health

MONKEY_PAW, "Spawns a red heart when damaged at low health

LOCUST_OF_WRATH, "Spawns an explosive locust when taking damage

LOCUST_OF_PESTILENCE, "Spawns a poison locust when taking damage

LOCUST_OF_FAMINE, "Spawns a slowing locust when taking damage

LOCUST_OF_DEATH, "Spawns a black locust when taking damage

LOCUST_OF_CONQUEST, "Spawns 2 white locusts when taking damage

CRICKET_LEG, "Spawns a random locust when taking damage

MOTHERS_KISS, "Charm enemies for 5 seconds when damaged

ICE_CUBE, "Chill nearby enemies when damaged

AZAZELS_STUMP, "Brimstone curse nearby enemies when damaged

SAMSONS_LOCK, "1/3 chance to activate Berserk! when damaged

BLIND_RAGE, "1/3 chance to activate Crack the Sky when damaged

CANCER, "Spawn a friendly Small Teratoma for the room when taking damage

BROKEN_REMOTE, "Teleport a bobby bomb inside an enemy when taking damage

CARTRIDGE, "5% chance to activate The Gamekid when damaged #Nintendo references increase activation chance by +5%

BOBS_BLADDER, "Bombs spawn a puddle of creep when they explode

BLASTING_CAP, "Bombs spawn a bomblet that deals 50% damage

SHORT_FUSE, "Bombs deal 33% more damage

MISSING_PAGE, "Necronomicon effects spawn a friendly Bony

MYSTERIOUS_PAPER, "Books are more powerful #Shops sell books

TEMPORARY_TATTOO, "Challenge rooms are always open #Enemies inside have doubled health

USED_DIAPER, "Charm fly enemies for 5 seconds when they spawn

TICK, "Charm spider enemies 5 seconds when they spawn

BROKEN_SYRINGE, "+5% damage per syringe item

SHINY_ROCK, "Breaking a tinted rock grants half a soul heart

LUCKY_ROCK, "33% chance to spawn a friendly rock spider when breaking a rock

JUDAS_TONGUE, "Taking a devil deal grants half a black heart

DEVILS_CROWN, "Items that cost heart containers restock

YOUR_SOUL, "Grants a soul heart when sold

STORE_CREDIT, "Uses Coupon when used

FRIENDSHIP_NECKLACE, "50% chance to replace shop item with familiar #Gives familiars spectral

RC_REMOTE, "50% chance to replace shop item with familiar #Gives familiars spectral

???_SOUL, "Shoots Continuum tears

ISAACS_HEAD, "Shoots bouncy tears

EVES_BIRD_FOOT, "Bird familiars apply fear on contact

UMBILICAL_CORD, "Gemini applies charm on contact #Little Steven gains Continuum

BAG_LUNCH, "Food items heal all red hearts

BLACK_TOOTH, "Black teeth spawn a poison cloud on collision with enemies

JAW_BREAKER, "Teeth spawn a bone spur on collision with enemies

BROKEN_PADLOCK, "Key pickups are replaced by bomb pickups

HOLY_CROWN, "Shops on new levels are replaced by Stairway shops

WICKED_CROWN, "Shops on new levels are replaced by devil deals

STORE_KEY, "Shops on new levels are level 5 shops

SILVER_DOLLAR, "Shops on new levels are level 5 shops

RIB_OF_GREED, "Shops on new levels are Tainted Keeper shops

FADED_POLAROID, "Shops on new levels are replaced by clean bedrooms

DAEMONS_TAIL, "New soul and red heart containers turn into black hearts

PAY_TO_WIN, "Donation machines are replaced by restock machines