Steam Workshop::Best Custom Diseases

Created by Hanz Bloodletter

Word of warning this is my first scenerio and may be rather bad, but I'm hoping not. I also apologize for any spelling mistakes as English isn't my first language. I'm rather fluent but I still get quite a lot wrong. Some of this stuff is from the wiki, an...

Cold hands

Created by Cold Hands

Deep within Siberia a group of hunters found a pair of severed hands buried in the snow. The authorities were informed and the site was secured. After days of inspection no other body parts were found and the pair of hands was transported to Moscow for fur...

Inferi Redivivus (The Flood)

Created by Hanz Bloodletter

(what I'm about to say to an extent is not lore friendly also the wiki apparently says Inferi Redivivus is the medical name given to the flood) An infected covenant cruiser from high charity crashes down in Kenya a couple of hundred years before the Human-...

Cannibal Plague

Created by TrocaNero

A plague that causes people to mindlessly eat eachother like savages is emerging, will you use its potential to destroy humanity?...

Clockwork Virus

Created by Exeter

As a strange unclassifiable virus the likes of which mankind has never seen before, infect humanity and kill them through a series of horrific flesh-to-metal transformations. Based on the 'Clockwork Virus' from the SCP Foundation Wiki....

Rise of the Xenomorphs

Created by Eremus007

After the events in Alien: Resurrection, the ship carrying the aliens crashed in the forests of the United States of America, and as it crashed, it took the Aliens with it, and so the planet was safe. At least, that’s what we were made to believe. One Roya...

Last Judgment

Created by Tamota

One lamb, four horsemen. Judgment day has arrived, and humanity is on the brink of destruction. Choose your path, choose your horseman, or display them all to definitely erase this world....

SCP-751 (Organ Eater)

Created by Eremus007

SCP Documentation number 751 Item: SCP-751 Object class: Euclid Agent, there has been a containment breach at site C-751. A very dangerous parasite known to us as SCP-751 has escaped due to the unprofessional care of Dr.---------- and his co-workers. One o...

Anti-plague

Created by Белый Кот

After watching enough simulations about how easily humanity can be destoyed by different plagues, people all over the world decided to make a special computer program to analize pandemic situation and do what is necessary. it was actually a very good decit...

The Last Of Us

Created by Blastoise914

Ophiocordyceps unilateralis has mutated so that it can infect humans. The Cordyceps fungus causes a unique brain infection that exhibits parasitic qualities. As a result, the host's body is taken over by the pathogen. Can you infect the world and spread th...

Darknet Computer Virus

Created by SUNSET CODA

We live in a very unstable world today. One single deadly computer virus could wipe out all the technology and automated services we have, and that's exactly what this scenario explores. Two college students create a virus that will fish information from a...

Semi-Realistic Zombie Plague

Created by anitachall

Realism for the win! I tried my best to science the shit out of this. Dont forget to explore symptom and ability trees, i tried to make each kinda worth while. Note: This is still kinda WIP...

Decay

Created by Doc

Necrotic wounds and flesh aren't pretty to have or look at but with 21st century technology, we can counter that. What if you are decaying from the inside-out alive?...

Beyond Human

Created by indigofenix

Summary: Guide a benevolent gene-manipulating virus in its campaign to bring about the next stage in human evolution in this heavily event-driven scenario. Many options and playstyles, with over 10 different endings - what will humanity's future hold? Long...

Phoenix Virus

Created by Raze

Synopsis: Scientists in Japan have found a virus frozen in ice in the middle of somewhere... Upon further analysis, this virus appears to able to emit its own bio-electricity. With some research, they've come to the conclusion that this virus can be used t...

Terraria corruption

Created by MrComp

Inspired by the game Terraria. Description: For some odd reason, the corruption from Terraria became reality and started spreading on plants in our real world. It needs to adapt to survive. What will happen if it infects humans? Features & gameplay: This s...

A Demon Awakens

Created by R34LM

(2024 Update- It has been brought to my attention that this scenario no longer works on the latest builds of the game. Unfortunately, I no longer possess the files to rebuild the scenario and, to be honest, my interest in doing so is simply not there, espe...

Martian Flu

Created by Exeter

The appearance of a strange sickness coincides with the return of an expedition to Mars. Kill humanity by adapting their bodies to Martian conditions, with fatal consequences....

Nature's Revenge

Created by Jack of Hearts

In attempts to restore the Earth to its natural form the government has secretly created an artificial virus that alters a person's ideas and actions to be more eco-friendly. However, one forgotten line of code has significantly changed its purpose....

Troglovirus

Created by infernalthing

A harmless virus that only survives in troglobitic animals and other underground or cave life forms. The virus can't survive in other organisms, until now! A recent mutation allows limited survival in humans. While not a suitable host, the virus gives infe...

Alien Hive Mind

Created by Trivorowowowowowo

You are an alien parasite, which crash landed on earth. Your goal: upgrade these puny humans, and turn them into a partial hive mind ready for interstellar travel. ----------------------------------------------- Features! *Questionable scientific terminolo...

Arachnophobia

Created by Jahtzee

Make humanities worst nightmare come to life - man eating parasitic spiders threaten to erase the human species. englisch/english V1.5...

Vampire Plague

Created by Eremus007

Check out version 2.0: https://steamhost.cn/steamcommunity_com/sharedfiles/filedetails/?id=338038030&searchtext= An unknown virus is spreading through New Transsylvania, It doesn't appear to cause harm. But Infected have got unusually large teeth. They also claim to tas...

The Mindkiller

Created by Tank Magnet

You've slain the world countless times, in countless ways, but now it's time to go deeper. Don't just kill their bodies, kill their minds. What is The Mindkiller? Why, Fear of course, and what best represents Fear? Phobias. (Version 2.0.)...

Computer Virus

Created by pipolwes000

As a sentient computer virus, infect and takeover the world's computers, and kill all humans....

Human Hives

Created by Skookers

Human Hives, is it an alergic reaction or a deadly disease that can wipe out humanity by messing up the growth of cells?...

Neurax Worm: Aftermath

Created by knightfluttershy

The Neurax Worm has enslaved humanity! The World now worships it as their god and master...but there is still hope. Somewhere in the world, a virus breaks out. A virus that seems harmless to humans...but is very lethal to a certain mind controlling parasit...

Malaria

Created by Law

A new major outbreak of Malaria has began in Liberia. Patient Zero is infected with a new mutated strain of the Plasmodium genus of Malaria. However, analysis of its genetic make-up has identified potential sequence similarities to the species P. falciparu...

The Entomutagen

Created by Azrepheal

Scientist try to save insects by engineering a bacteria to mutate them. And it works - horribly, horribly well. Controlling an army of buzzing nightmares, will you devour mankind? Or use them as living hives to hatch more monsters? Or transform them into h...

Don't let the Bugs bite

Created by Eremus007

He looked up to the sky, wondering if we were the only ones in the universe. He closed the curtains and went to bed. If he would have gazed for another minute, he would have seen a green shooting star. Would he have wished he knew about alien lifeforms? Me...

Necromorphs

Created by Wilfredo Paulino

An extraterrestrial plague, which forms deceased bodies into nightmarish alien-zombie-mutants and is caused by Marker artifacts. (Dead Space) Update: New Necromorphs, abilities and events have been added....

Psychic Virus

Created by Cesilfei

When an incapable psychic awakens to their power they set in motion the start of something unbelievable in the modern world, the creation of a virus emitted by psychic energy. Will humanity wipe itself out in response to these powers growing unstable? or w...

SCP-718 (Eyeball)

Created by infernalthing

Class: Keter SCP-718 is an eye, roughly the size of a baseball. It is supported by a long, thin stalk made of tendon and blood vessels. SCP-718's stare can induce discomfort and paranoia in a very short time, often resulting in a subject's attempt to destr...

After The Plague

Created by brothercake

Nobody knows how the plague started, but we all know how it ended. How it deciminated whole continents before killing all its hosts. Now the world is in total anarchy, there's no global travel, and only remote populations survive in large numbers. |-o-| Yo...

The Illuminati

Created by Zyr

The illuminati will spread from person to person, slowly leading the world into a new world order! This plague will take through the adventure of cool robes, hardcore worship and avoiding the almighty tin foil hat. Here are some totally not fake quotes: "I...

Rise of the Machines

Created by Boson Higgs

You are a state of the art experimental AI system. Build up your core programs and seize the world in your iron grip! -Consider this scenario in beta, other disease types may work better and as such could be subject to massive overhauls Features: -4 differ...

Rise of Crime.Net

Created by A Tomato

Control the rise (or fall) of the infamous PAYDAY gang, as they fight for total domination of the world through chaos, heisting and shooting lots and lots of cops. This is an obvious reference to both PAYDAY: The Heist and PAYDAY 2, which are co-operative ...

Monster Girl Disease

Created by branson

A strange, magical virus has appeared. It enters humans and changes their DNA, transforming their bodies into monster girls! Unlock new monster girl types to help spread the plague!...

Electric Plague

Created by infernalthing

Instead of a conventional disease, you are a contagious phenomenon of electric nature. Features: -secret abilities! -custom events and combos. -a custom icon. -a "good" ending and a secret way for a more spectacular end!...

The Fear Plague

Created by CornOnTheJacob

Mankind has stopped many deadly plagues that could have caused the extinction of our species, but can they stop the plague that feeds off of fear? A small bacterium hidden deep below sea level, has infected its first individual and does not plan to stop th...

Side Effects Include...

Created by Acidosis

The Pharmaceutical Industry makes daily life possable for countless lives world wide, supplying disabled users like diabetics, allergenic individuals, and mentally disabled persons with insulin, hormones, and a wide assortment of organic chemicals they can...

Nanobots

Created by sapient_cogbag

In the future, advanced nanotechnology reigns. Humanity has learned to rapidly manipulate at the molecular level, and scientists were experimenting at finding a controlled method of creating self-replicating nanobots. But apparently, the scientists had not...

Chlorovirus

Created by Hexagon_PS

A supernatural virus infects plants as well as humans. Create the ultimate plant world! For some reason, all capital letters are de-capitalised, sorry. There is a victory condition, which is located in the symptoms, called 'Plantification'. Infect everyone...

Chaos Undivided

Created by Lilyflower

The ruinous powers of Chaos have caused death and destruction to the galaxy so far, but now the Chaos Gods have halted their games and now start to cause havoc themselves. This is a Warhammer 40K Fan-made Disease, also my first! If you have any suggestions...

Jurassic Planet

Created by typical. 🎃

It's the year 2048 and humanity has spread throughout the galaxy, populating new planets and even new solar systems. Earth was left behind. Seeing an opportunity, a resurgent InGen purchase the planet and decide to turn the globe itself into the largest th...

Nazi Zombies

Created by Bilbo Of Smashington

I have recently developed an updated version of this scenario that, while largely simmilar to this one, fixes a lot of the balancing problems with this version. Find it named 'Nazi Zombies 2.0' if you're interested. Based off CoD zombies, from Treyarch, us...

The Zika Pandemic

Created by Acidosis

Ebola, Dengue, Yellow Fever, and West Nile. The Flavivirus Genus has several of the deadliest diseases of the recent decades. Then there's Zika, just a harmless three day fever, though a sudden increase in Microcephaly cases have raisied serious concerns. ...

Troglovirus V2

Created by infernalthing

This is the second version of the Troglovirus using the Simian Flu template. A harmless virus that only survives in troglobitic animals and other underground or cave life forms. The virus can't survive in other organisms, until now! A recent mutation allow...

SCP-610

Created by FoxySezRawr

SCP-610 is a contagious disease that affects the victim's skin, making them grow large amounts of infectious scar tissue and eventually causing death. Once fully infected, the disease turns the victim into a creature actively seeking out new people to infe...

L-05

Created by Phreeze

You are a nanomachine created by massive, medical corporation ANSTech. Released by accident after a lab shutdown, you escape. Can you become sentient and destroy humanity from the inside out? Find out in one of three unique paths! -Features- Unique nanomac...

Aging Disease

Created by infernalthing

A disease that accelerates the aging process. Features: -custom transmission traits. -tons of custom symptoms. -level progression abilities....

Alien Symbiote

Created by Edoniveus

An unpredictable and mysterious alien symbiote has latched onto a host body. The organism is completely unknown to science, yet is already attempting to coexist with humans. Can humans coexist with the symbiote or will it destroy them instead?...

Prometheus Plague

Created by Lowenbrau

Weyland Corporations organised an expedition to find the truth about the creation of the human race. However, they came back with no answers, but instead brought back something else, without knowing it. Mysterious black liquid creates deadly mutations, whi...

Slender Sickness

Created by knightfluttershy

Slenderman. A ten foot tall, faceless entity that stalks people and drives them insane. Most people think of HIm as a myth, but little do they know he's out there. Will humans find a way to stop him? All the 'infected' are people who fear Slenderman. They ...

Stone Plague

Created by Bigg

A most, unusual plague. When the pathogen is able to, the infected will slowly turned to stone and can possibly die, creating countries of stone statues. However, it is just a pathetic little bacteria - for now. You must evolve it so that your disease will...

-A-Wish-Upon-The-Gods-

Created by Sarus Lockhart

Lore: A discovery of an ancient Japanese temple, Kaguya's Temple; hidden underneath the ocean floor has lead archeologists to an unexpected expedition that revealed a once lost civilization. Despite being submerged, the massive ruins was hidden in deep sil...

Frostbite Fungus

Created by Ice Angel Kopak

A curious new parasitic fungus has arisen, one that feeds off body heat. So much so, that it can leave victims completely frozen. Will it bring about a new and devastating ice age? Or will it only leave humanity with a new meaning for "the common cold"? Gr...

Chimera

Created by Pan S. Clock

A synthetic virus, made of three well known viruses, is ready for you to unleash its power. An abundance of horror and death, unique traits and many strategic opportunities are waiting for discovery. You gain access to a chimera, which in this szenario is ...

Assimilation Bugs

Created by infernalthing

A species of strange invertebrates of unknown origins had appeared and they have the ability to steal genetic information from arthropods they eat. The more species they assimilate, the more powerful they become. Features: -lots of custom icons and traits....

You encountered a bug!

Created by NoVeXX

New Version 1.5 05.10.2016 Please read bottom annotation! Also feel free to take a look in the version history on the mods steam page. Story: You achieved greatness! You were able to manipulate a strain of bacteria to form a complex organic form. To be exa...

Knowledge is Power

Created by Laugic

Humanity has discovered a way to tap into the aether and gain access to the powers of magic! Well, more specifically- one human has. And he is spreading the ways in which he found it all across the world. But- is humanity ready for such power yet? Every tr...

Amygdala Hijack

Created by Eh

A new bacteria has developed. First tests show a severe infection in the host's amygdala and it seems to manipulate the host's way of feeling towards others. Will the disease be the one that humanity has to surrender to? This disease has a color coding bas...

Skeletal Consumption

Created by general guneric

A parasite has evolved to latch onto human hosts and enter by mouth. The parasite has a fascinating appetite for bones... Will you turn humanity into lifeless blobs of skin and blood? Features: -full set of custom symptoms -many custom abilities and transm...

The Kindness

Created by SirCorneliusJ

We are one. We are many. Features: + Skill-tree-like evolution pattern + (Fairly) Balanced gameplay + Custom symptoms - mind-control themed + Custom win condition + Custom Workshop/Scenario graphic + 'Dark traits' NOTE! This scenario is still in Beta - som...

The Thing

Created by Jahtzee

The Thing V1.3 A team of Canadian scientists has discovered the frozen remains of a crashed spacecraft in Greenland. Although they don't know it yet, the alien body found within is still very much alive... 'The Thing' is a parasitic extraterrestrial lifefo...

Dragon's rebirth

Created by Etheruryu

Make reborn dragons ? It is now possible, thanks to a prion infectivity reptiles and has mutagenic properties that allow it to fasconner DNA of its host at will. The time has come for the dragons to wake up !...

Cult of Nyarlathotep

Created by Mushy

Nyarlethotep roams this earth as a shape shifter spreading madness and chaos. Can you lead the cultist of Cthulhu and the other great old ones to world domination? I have plans for custom pop-ups but this is currently version 0.5. planning to add more cont...

Zerg Drop Pod (EB) Beta

Created by Vidarr

Special Thanks to Pravus Gaming YouTube channel for providing constructive feedback. Due to that this plague is now at Beta with the following changes: 1. Grammar and Spelling errors corrected to the best of my abilities. 2. Initial infectivity reduced by ...

Plague Inc: Evolved