Not sure where you pulled that from, but it isn't an error log and half of the mods you have listed there don't reference Alpha Genes in any way, shape, or form. exlcusionTags hasn't changed since 1.4, and if there were xml changes then they would've thrown errors when the game is launched with the mods active, which I have not reported. Also, you pasted it in the completely wrong series, let alone wrong mod(s)

2.1 Out‑of‑date “More … Genes” mini‑mods
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[More Pain Genes] PatchOperationReplace … failed
[More Psychic Sensitivity Genes] PatchOperationReplace … failed
[More Study Genes] … failed
[More Toughness Genes] … failed
[More UV Sensitivity Genes] … failed
These patches are written against Alpha Genes 1.4 / vanilla Biotech genes pre‑1.5.
RimWorld 1.5 changed gene XML structure (new tags, reordered lists). The patches can no longer find the nodes they expect, so they fail and later throw null‑reference errors (nullifyingGenes list later in the log).

Fix

Remove the individual “More … Genes” addons – all of their content is now part of Alpha Genes itself.

Or update to the 1.5‑ready versions if the author has released them (check Steam Workshop changelog).

Added 6 new numbness genes

An All in One has been made . It will be updated in the future, but most of my planned easy genes have been made.