I have a BIG 1.5 modpack but this mod seems to be the source of save-break situation.
After switching game off and turning on again (doesn't matter if PC was shut down or not) all of my saves with this mod active, are corrupted - I can't start them because my game crashes during loading. I think it's the interaction between one of the other 500 mods out in my modpack but I have no time to check which one interacts in this way with infusion 2 - it could be one of the
incompatible mods that u mentioned in mod description.

Still I wanted to share that it can cause something like this - I was enabling and disabling different mods to see the effects for 3 days straight and I got my answer now, maybe someone else will use that knowledge...